care for Lupus

INCREASED PREVALENCE OF HEART ATTACKS IN LUPUS PATIENTS

Thursday, December 01, 2005

INCREASED PREVALENCE OF HEART ATTACKS IN LUPUS PATIENTS

Patients with systemic lupus erythematosus (SLE) have an increased prevalence of heart attacks according to studies in the New England Journal of Medicine. In one study 40% of lupus patients had atherosclerotic plaques, a precursor of heart problems. This could be due to the chronic activation of the immune system. Possible SLE-related risk factors include systemic inflammation, autoantibodies to endothelium cells that make up the inside of blood vessels, HDL, phospholipids, circulating immune complexes, activated complement products, nephritis (kidney disease), and dyslipidemia (disorders of HDL and LDL metabolism).

“Systemic Lupus Erythematosus and Accelerated Atherosclerosis”, Bevra Hannahs Hahn, MD, NEJM 349:25, December 18, 2003, P. 2379

Blogged on 8:54 PM

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