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Prematurity and Preeclampsia Complicate Lupus Pregnancies Saturday, November 05, 2005 Prematurity and Preeclampsia Complicate Lupus Pregnancies American Journal of Obstetrics and Gynecology 192:6, 1897-1904 (June 2005) This study of pregnancies in lupus patients over a 10-year period looked at 63 pregnancies in 48 women. Twelve pregnancies were complicated by preeclampsia (also known as toxemia, involving high blood pressure, weight gain, and protein in the urine after the 20th week of pregnancy). Rates of deaths of babies near the end of pregnancy or at the time of birth due to this condition are high. First-time pregnancies, African American background and a history of high blood pressure or kidney disease all increase the risk of preeclampsia, which makes this condition of special concern for women who have lupus. Currently, the only way to treat preeclampsia is to deliver the baby. However, complications can occur because of prematurity of an infant at time of delivery. The researchers in this study concluded that low platelet counts, high blood pressure, and the need for prednisone all may be predictive factors for problems occurring in pregnancies of women with lupus. Other factors found to be associated with premature delivery in lupus pregnancies included prednisone use at the time a woman gets pregnant, use of blood pressure medications, and a severe flare during pregnancy. Physicians managing lupus pregnancies, which are always considered high-risk, will want to monitor these factors in their patients. To read the complete abstract go to: http://www.mdlinx.com/Rheumatol
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